Diabetes and Endocrinology

Diabetes milletus associated microvascular complications appear particularly at higher risk of accelerated atherosclerosis which ultimately culminates in cerebrovascular and cardiovascular events and premature death. Micro vessels are the basic functional unit of the cardiovascular system comprising of arterioles, capillaries, and venules. They differ from macro vessels in both their architecture and cellular components. In contrast to macrovessels supplying blood to organs, microvessels play important roles in maintaining blood pressure and proper nutrient delivery. The microcirculation also has regulatory systems controlling vascular permeability and myogenic responses that can adapt blood flow according to local metabolic needs.